Topic: Salvestrols, including a brief introduction to CYP enzymes in drug metabolism, curcumin, with the main focus on its anti-inflammatory and anticancer actions; how to resist the advertising blandishments of health supplement manufacturers and distributors
Dan Burke, Emeritus Professor of Pharmaceutical Metabolism, is Head of Research for Salvestrol Natural Products Ltd., in Syston, Leicester, UK. With a First Class Honours BSc degree in Biochemistry from London University, a PhD in Drug Metabolism from the University of Surrey, an international university career spanning thirty five years and over 200 published research articles to his name, Professor Burke is an expert on the metabolism, toxicity and interactions of drugs, environmental chemicals and natural compounds. His specialism is the Cytochrome P450 or CYP enzyme system, which he has researched in species as diverse as humans and citrus fruits. Cancer – its causation, detection, prevention, and treatment - has formed a consistent thread throughout his research and teaching, which includes nearly twenty years on the science faculty of Aberdeen University medical school.
In the 1970’s Professor Burke invented a set of biochemical tests that are used worldwide in the biomonitoring of environmental pollution and by the pharmaceutical industry in drug discovery and development (the EROD Assays). In the 1990’s he and his research group discovered that cancer cells contain a unique enzyme, CYP1B1, which is now a worldwide focus of research into new methods of cancer detection, prevention, and treatment.